One Mind Ketamine - Physician-Led IV Ketamine Therapy in South Florida

For people who’ve done the work—and still feel stuck. Board-certified anesthesiologist-guided treatment for depression, anxiety, PTSD, and chronic pain that works alongside your existing care team.

We Created One Mind for a Reason

We built this practice for patients who’ve been told, “There’s nothing left to try.” But there is—when it’s done the right way: physician-led, research-backed, and built around real outcomes.

Most of our patients come to us after exhausting meds, therapy, or pain treatments that didn’t stick. We believe true healing happens when science meets compassion—and the goal is actual transformation.

What makes us different:
physician

Guided by a board-certified anesthesiologist and pain management physician

treatment rooms

Private, discreet treatment rooms designed for healing, not hurry

protocols

Research-backed protocols with personalized dosing

care team

Works alongside your therapist, psychiatrist, and care team

Patient Reviews

Real People, Real Results
Best money I’ve ever spent. Ketamine therapy helped quiet my racing thoughts and gave me a sense of peace I hadn’t felt in a long time. I’m sleeping better, getting out of bed with more energy, and I finally feel like I have my motivation back to focus on building my business. The entire team is incredibly kind, compassionate, and professional. They made me feel comfortable and, most importantly, safe throughout every session. I’m truly grateful for this experience and highly recommend this clinic to anyone looking for real support on their healing journey.
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Racquel J.
7/14/2026
I had an exceptional experience at One Mind Wellness and cannot recommend them highly enough. I was very nervous heading into my first session as I’m working through a lot of grief but from the moment I arrived I felt genuinely supported and cared for. Mike the concierge was incredibly kind and attentive and made sure I felt fully prepared and comfortable throughout the process. Dr. Topfer was extremely hands-on compassionate and thoughtful creating such a safe and reassuring environment. Even after my first session I noticed a sense of relief which has given me so much hope for the journey ahead. The entire team goes above and beyond to make the experience feel supportive professional and truly patient centered and I’m very grateful to have found them.
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Alexa D.
3/17/2026
I had an exceptional experience at One Mind Wellness, and I cannot recommend them highly enough.From the moment you walk in, you feel supported and cared for. Mike, the concierge, is wonderful — incredibly attentive, kind, and helpful throughout the entire process. He truly makes you feel comfortable and welcomed.Dr. Topfer and Dr. Greca are a top-notch team. Their professionalism, knowledge, and compassion made me feel that I was in the best possible hands. My neuropsychiatrist actually recommended ketamine therapy to me, which is what led me to One Mind Wellness, and I’m so grateful that I followed that advice.I completed six ketamine sessions, and the results have been life-changing. Before treatment, I struggled with rumination — my thoughts often felt stuck in a negative loop that I couldn’t break. Since completing the sessions, that pattern has lifted. I feel calmer, much less reactive, and more at peace mentally.I’ve also noticed improvements in my energy and my ability to focus. It truly feels like my mind has reset in a healthy way.My only regret is that I didn’t do this sooner.If you are considering ketamine therapy, you will be in excellent hands at One Mind Wellness.
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Kellie S.
3/08/2026
Dr. Graca and team are really top notch. I run a large healthcare company and know the industry well and these guys really go the extra mile. Ketamine saved me and I was so worried when moving from NYC, but Graca talked to all my other doctors and took great care of me
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Connor W.
12/24/2025
5 star ratingI recently completed a six-session treatment at OneMind Ketamine, and I can't say enough good things about it. From the very beginning, the experience was welcoming and reassuring. The two anesthesiologists on staff had an incredible bedside manner: they took the time to explain every step of the process, all the science behind it, and really made sure I felt comfortable and informed. They were compassionate and patient throughout, which really stood out to me.

A big shoutout also goes to Mike, the case coordinator. He was there for me every step of the way, from the initial interview (with zero pressure) to all the follow-ups before and after sessions. He provided so much support and reassurance that I never felt alone in the process.
Overall, the entire six-session journey has been incredible. I've noticed meaningful progress in different areas of my life, not just during the sessions but in the days and weeks after them. I find myself reflecting on what I experienced and how it's reshaping my habits and perspectives.

If you're considering ketamine therapy, I'd highly recommend at least doing an intake with OneMind. Having recently relocated to South Florida, this experience has felt like a perfect "reset" button and really confirmed my decision to start a new chapter here.
Thanks to the whole team at OneMind for their exceptional care!
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Josh K.
12/05/2025
If you're looking for a very professional Doctor administered treatment this would be the place. Cutting edge anesthesiologist's perform the service which I found way more comforting than a nurse practitioner.
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Mark H.
10/17/2025
mental health near me fort lauderdale, fl

Ketamine Therapy for Mental Health

IV ketamine therapy disrupts rigid thought loops and helps your brain form new, healthier patterns. It’s not just symptom relief—it’s a reset.

Most patients notice a shift within the first few sessions, with significant benefits emerging across our full 6-session protocol.

We Treat:
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Ketamine Treatment for Chronic Pain Management

When pain has become your identity, ketamine for pain helps you reclaim space. Our physician-guided infusions work on the brain’s glutamate system and calm the alarm network that keeps pain signals firing.

We Treat:

The Gold-Standard Protocol Matters

IV ketamine, delivered in a structured six-infusion series, is the safest and most consistent way to support meaningful change. It’s the approach used by leading physicians because it offers precision, stability, and fully monitored care—without shortcuts.

iv
IV Only — Precise and Predictable

IV delivery allows exact dosing and real-time adjustment. No lozenges. No at-home use. No unpredictable absorption.

structure
Six-Infusion Structure

A series of six treatments over 2–3 weeks gives the brain repeated windows of neuroplasticity. Most patients notice shifts between sessions 3–5 as patterns begin to loosen.

fully monitored
Physician-Led and Fully Monitored

Every infusion is overseen by board-certified anesthesiologists. Blood pressure, heart rate, and oxygen levels are monitored throughout—every appointment.

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How Ketamine Creates Lasting Change

Ketamine helps disrupt rigid thought loops. It’s not just symptom relief, it’s a reset.

It works on the brain’s glutamate system, calms the brain’s alarm network, and helps your mind form new, healthier patterns. Each protocol is guided by our Co-Medical Directors, Dr. Matt Graca and Dr. Jacob Topfer—both board-certified anesthesiologists and pain management physicians with advanced fellowship training at the University of Miami.

We deliver precision treatment in a calming, private space where you’re monitored throughout every session. We partner with therapists, psychiatrists, and care teams to enhance—not compete with—your treatment plans.

One Mind represents balance—bringing together the conscious and subconscious, science and spirituality, self and community.

Ready to Move Forward?

Tell us your story. We’ll map the path forward.

We’ll listen, understand your needs, and see if ketamine therapy is the right fit. No pressure. No obligations. Just support, guidance, and clear answers.

Contact Us: 954-870-4768